HMM Summary Page: TIGR01654

Functionbacteriocin-associated integral membrane protein
Trusted Cutoff189.35
Domain Trusted Cutoff189.35
Noise Cutoff176.55
Domain Noise Cutoff176.55
Isology Typesubfamily
HMM Length681
Mainrole CategoryCellular processes
Subrole CategoryToxin production and resistance
AuthorHaft DH
Entry DateAug 29 2002 2:22PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a family of integral membrane proteins, most of which are about 650 residues in size and predicted to span the membrane seven times. Nearly half of the members of this family are found in association with a member of the lactococcin 972 family of bacteriocins (TIGR01653). Others may be associated with uncharacterized proteins that may also act as bacteriocins. Although this protein is suggested to be an immunity protein, and the bacteriocin is suggested to be exported by a Sec-dependent process, the role of this protein is unclear.
ReferencesRM 10589723 RT Synthesis of lactococcin 972, a bacteriocin produced by Lactococcus lactis IPLA 972, depends on the expression of a plasmid-encoded bicistronic operon. RA Martinez B, Fernandez M, Suarez JE, Rodriguez A. RL Microbiology 1999 Nov;145 ( Pt 11):3155-61
Genome PropertyGenProp0809: bacteriocin system, lactococcin 972 group (HMM)