HMM Summary Page: TIGR01612

Functionrhoptry protein
Trusted Cutoff1615.85
Domain Trusted Cutoff1615.85
Noise Cutoff1508.80
Domain Noise Cutoff1508.80
Isology Typeparalog
HMM Length2756
AuthorSelengut J
Entry DateJul 30 2002 11:56AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite [1,2]. These proteins are found in P. falciparum, P. vivax and P. yoelii.
ReferencesRN [1] RM PMID: 11551627 RT The 235 kDa rhoptry protein of Plasmodium (yoelii) yoelii: function at the junction. RA Khan SM, Jarra W, Preiser PR. RL Mol Biochem Parasitol 2001 Sep 28;117(1):1-10 RN [2] RM PMID: 10637585 RT Malaria multigene families: the price of chronicity. RA Snounou G, Jarra W, Preiser PR. RL Parasitol Today 2000 Jan;16(1):28-30