HMM Summary Page: TIGR01608

Functioncitrate lyase acyl carrier protein
Gene SymbolcitD
Trusted Cutoff63.50
Domain Trusted Cutoff63.50
Noise Cutoff35.05
Domain Noise Cutoff35.05
Isology Typeequivalog
EC Number4.1.3.6
HMM Length94
Mainrole CategoryEnergy metabolism
Subrole CategoryFermentation
Gene Ontology TermGO:0006113: fermentation biological_process
GO:0008815: citrate (pro-3S)-lyase activity molecular_function
GO:0009346: citrate lyase complex cellular_component
AuthorDurkin S
Entry DateJul 29 2002 4:11PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis is a model of the acyl carrier protein (aka gamma subunit) of the holoenzyme citrate lyase (EC composed of alpha (EC, beta (EC, and acyl carrier protein subunits in a stoichiometric relationship of 6:6:6. Citrate lyase is an enzyme which converts citrate to oxaloacetate. In bacteria, this reaction is involved in citrate fermentation. The acyl carrier protein covalently binds the coenzyme of citrate lyase. The seed contains an experimentally characterized member from Leuconostoc mesenteroides [1]. The model covers a wide range of Gram positive bacteria. For Gram negative bacteria, it appears that only gamma proteobacteria hit this model. The model is quite robust with queries scoring either quite well or quite poorly against the model. There are currently no hits in-between the noise cutoff and trusted cutoff.
ReferencesRN [1] RM PMID: 9457870 RT Purification of Leuconostoc mesenteroides citrate lyase and cloning and characterization of the citCDEFG gene cluster. RA Bekal S, Van Beeumen J, Samyn B, Garmyn D, Henini S, Divies C, Prevost H RL J Bacteriol 1998 Feb;180(3):647-54 DR HAMAP; MF_00805; 58 of 59
Genome PropertyGenProp0672: citrate lyase system (HMM)