HMM Summary Page: TIGR01606

Functionholin, BlyA family
Trusted Cutoff52.85
Domain Trusted Cutoff52.85
Noise Cutoff44.00
Domain Noise Cutoff44.00
Isology Typeequivalog
HMM Length63
Mainrole CategoryMobile and extrachromosomal element functions
Subrole CategoryProphage functions
AuthorHaft DH
Entry DateJul 26 2002 5:36PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family represents a BlyA, a small holin found in Borrelia circular plasmids that prove to be temperate phage. This protein was previously proposed to be an hemolysin. BlyA is small (67 residues) and contains two largely hydrophobic helices and a highly charged C-terminus.
ReferencesRM 11073925 RT Characterization of Borrelia burgdorferi BlyA and BlyB proteins: a prophage-encoded holin-like system. RA Damman CJ, Eggers CH, Samuels DS, Oliver DB. RL J Bacteriol 2000 Dec;182(23):6791-7
Genome PropertyGenProp0208: phage: major features (HMM)