| Accession | TIGR01588 |
| Name | citE |
| Function | citrate (pro-3S)-lyase, beta subunit |
| Gene Symbol | citE |
| Trusted Cutoff | 443.40 |
| Domain Trusted Cutoff | 443.40 |
| Noise Cutoff | 337.30 |
| Domain Noise Cutoff | 337.30 |
| Isology Type | equivalog |
| EC Number | 4.1.3.6 |
| HMM Length | 288 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Fermentation |
| Gene Ontology Term | GO:0006113: fermentation biological_process |
| | GO:0008815: citrate (pro-3S)-lyase activity molecular_function |
| | GO:0009346: citrate lyase complex cellular_component |
| Author | Durkin S |
| Entry Date | Jul 16 2002 3:53PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This is a model of the beta subunit of the holoenzyme citrate lyase (EC 4.1.3.6) composed of alpha (EC 2.8.3.10), beta (EC 4.1.3.34), and acyl carrier protein subunits in a stoichiometric relationship of 6:6:6. Citrate lyase is an enzyme which converts citrate to oxaloacetate. In bacteria, this reaction is involved in citrate fermentation. The beta subunit catalyzes the reaction (3S)-citryl-CoA = acetyl-CoA + oxaloacetate. The seed contains an experimentally characterized member from Leuconostoc mesenteroides [1]. The model covers a wide range of Gram positive bacteria. For Gram negative bacteria, it appears that only gamma proteobacteria hit this model. The model is quite robust with queries scoring either quite well or quite poorly against the model. There are currently no hits in-between the noise cutoff and trusted cutoff. |
| References | RN [1]
RM PMID: 9457870
RT Purification of Leuconostoc mesenteroides citrate lyase and cloning and characterization of the citCDEFG gene cluster.
RA Bekal S, Van Beeumen J, Samyn B, Garmyn D, Henini S, Divies C, Prevost H
RL J Bacteriol 1998 Feb;180(3):647-54 |
| Genome Property | GenProp0672: citrate lyase system (HMM) |
