HMM Summary Page: TIGR01567

FunctionS-layer family duplication domain
Trusted Cutoff121.90
Domain Trusted Cutoff121.90
Noise Cutoff84.45
Domain Noise Cutoff84.45
Isology Typesubfamily_domain
HMM Length259
Mainrole CategoryCell envelope
Subrole CategorySurface structures
AuthorHaft DH
Entry DateJun 26 2002 2:30PM
Last ModifiedSep 22 2011 11:20AM
CommentThis HMM represents a sequence region found tandemly duplicated in two proven archaeal S-layer glycoproteins, MA0829 from Methanosarcina acetivorans C2A and MM1976 from Methanosarcina mazei Go1, as well as in several paralogs of those L-layer proteins from both species. Members of the family show regions of local similarity to another known family of archaeal S-layer proteins described by model TIGR01564. Some members of this family, including the proven S-layer proteins, have the archaeosortase A target motif, PGF-CTERM (TIGR04126), at the protein C-terminus.
ReferencesRN [1] RM PMID:19228054 RT S-layer, surface-accessible, and concanavalin A binding proteins of Methanosarcina acetivorans and Methanosarcina mazei. RA Francoleon DR, Boontheung P, Yang Y, Kin U, Ytterberg AJ, Denny PA, Denny PC, Loo JA, Gunsalus RP, Loo RR RL J Proteome Res. 2009 Apr;8(4):1972-82.