HMM Summary Page: TIGR01559

Functionfarnesyl-diphosphate farnesyltransferase
Trusted Cutoff286.75
Domain Trusted Cutoff286.75
Noise Cutoff127.80
Domain Noise Cutoff127.80
Isology Typeequivalog
EC Number2.5.1.21
HMM Length337
AuthorHaft DH
Entry DateJun 19 2002 12:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes farnesyl-diphosphate farnesyltransferase, also known as squalene synthase, as found in eukaryotes. This family is related to phytoene synthases. Tentatively identified archaeal homologs (excluded from this model) lack the C-terminal predicted transmembrane region universally conserved among members of this family.
ReferencesDR EXPERIMENTAL; SP|P37268; Homo sapiens DR EXPERIMENTAL; SP|P53799; Arabidopsis thaliana DR EXPERIMENTAL; SP|P29704; Saccharomyces cerevisiae DR OUTGROUP; SP|P22872; Phytoene synthase