Accession | TIGR01545 |
Name | YfhB_g-proteo |
Function | HAD hydrolase, family IF |
Gene Symbol | yfhb |
Trusted Cutoff | 259.25 |
Domain Trusted Cutoff | 259.25 |
Noise Cutoff | 204.50 |
Domain Noise Cutoff | 204.50 |
Isology Type | hypoth_equivalog |
HMM Length | 210 |
Gene Ontology Term | GO:0016787: hydrolase activity molecular_function |
Author | Selengut J |
Entry Date | Jun 12 2002 10:39AM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM describes a clade of sequences limited to the gamma proteobacteria. This group is a member of the haloacid dehalogenase (HAD) superfamily of aspartate-dependent hydrolases and all of the conserved catalytic motifs are present [1]. Although structurally similar to subfamily IA in that the variable domain is predicted to consist of five consecutive alpha helices (by PSI-PRED), it is sufficiently divergent to warrant being regarded as a separate sub-family (IF).
The gene name comes from the E. coli gene. There is currently no information regarding the function of this gene. |
References | RN [1]
RM PMID: 7966317
RT Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity. Application of an iterative approac
h to database search.
RA Koonin EV, Tatusov RL.
RL J Mol Biol 1994 Nov 18;244(1):125-32 |