| Accession | TIGR01498 |
| Name | folK |
| Function | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase |
| Gene Symbol | folK |
| Trusted Cutoff | 54.10 |
| Domain Trusted Cutoff | 54.10 |
| Noise Cutoff | 32.60 |
| Domain Noise Cutoff | 32.60 |
| Isology Type | equivalog |
| EC Number | 2.7.6.3 |
| HMM Length | 128 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Folic acid |
| Gene Ontology Term | GO:0003848: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity molecular_function |
| | GO:0009396: folic acid-containing compound biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | May 6 2002 5:12PM |
| Last Modified | Aug 12 2011 9:01AM |
| Comment | This HMM describes the folate biosynthesis enzyme 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. Alternate names include 6-hydroxymethyl-7,8-dihydropterin diphosphokinase and 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase (HPPK). The extreme C-terminal region, of typically eight to thirty residues, is not included in the model. This enzyme may be found as a fusion protein with other enzymes of folate biosynthesis. |
| References | DR PFAM; PF01288
DR INTERPRO; IPR000550 |
| Genome Property | GenProp0038: tetrahydrofolate biosynthesis from GTP and PABA (HMM) |
