HMM Summary Page: TIGR01496

Functiondihydropteroate synthase
Gene SymbolfolP
Trusted Cutoff162.60
Domain Trusted Cutoff162.60
Noise Cutoff92.70
Domain Noise Cutoff92.70
Isology Typeequivalog
EC Number2.5.1.15
HMM Length258
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryFolic acid
Gene Ontology TermGO:0004156: dihydropteroate synthase activity molecular_function
GO:0009396: folic acid-containing compound biosynthetic process biological_process
AuthorHaft DH
Entry DateMay 6 2002 11:08AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents dihydropteroate synthase, the enzyme that catalyzes the second to last step in folic acid biosynthesis. The gene is usually designated folP (folic acid biosynthsis) or sul (sulfanilamide resistance). This model represents one branch of the family of pterin-binding enzymes (PF00809) and of a cluster of dihydropteroate synthase and related enzymes (COG0294). Other members of PF00809 and COG0294 are represented by HMM TIGR00284.
ReferencesDR EXPERIMENTAL; SP|P05382; Streptococcus pneumoniae DR EXPERIMENTAL; SP|P19539; Plasmid pGS05
Genome PropertyGenProp0038: tetrahydrofolate biosynthesis from GTP and PABA (HMM)