| Accession | TIGR01496 |
| Name | DHPS |
| Function | dihydropteroate synthase |
| Gene Symbol | folP |
| Trusted Cutoff | 162.60 |
| Domain Trusted Cutoff | 162.60 |
| Noise Cutoff | 92.70 |
| Domain Noise Cutoff | 92.70 |
| Isology Type | equivalog |
| EC Number | 2.5.1.15 |
| HMM Length | 258 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Folic acid |
| Gene Ontology Term | GO:0004156: dihydropteroate synthase activity molecular_function |
| | GO:0009396: folic acid-containing compound biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | May 6 2002 11:08AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents dihydropteroate synthase, the enzyme that catalyzes the second to last step in folic acid biosynthesis. The gene is usually designated folP (folic acid biosynthsis) or sul (sulfanilamide resistance). This model represents one branch of the family of pterin-binding enzymes (PF00809) and of a cluster of dihydropteroate synthase and related enzymes (COG0294). Other members of PF00809 and COG0294 are represented by HMM TIGR00284. |
| References | DR EXPERIMENTAL; SP|P05382; Streptococcus pneumoniae
DR EXPERIMENTAL; SP|P19539; Plasmid pGS05 |
| Genome Property | GenProp0038: tetrahydrofolate biosynthesis from GTP and PABA (HMM) |
