HMM Summary Page: TIGR01485
| Accession | TIGR01485 |
| Name | SPP_plant-cyano |
| Function | sucrose phosphatase |
| Gene Symbol | SPP |
| Trusted Cutoff | 183.65 |
| Domain Trusted Cutoff | 183.65 |
| Noise Cutoff | 100.05 |
| Domain Noise Cutoff | 100.05 |
| Isology Type | equivalog |
| EC Number | 3.1.3.24 |
| HMM Length | 249 |
| Author | Selengut J |
| Entry Date | Apr 10 2002 10:20AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes the sucrose phosphate phosphohydrolase from plants and cyanobacteria (SPP). SPP is a member of the Class IIB subfamily (TIGR01484) of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. SPP catalyzes the final step in the biosynthesis of sucrose, a critically important molecule for plants. Sucrose phosphate synthase (SPS), the prior step in the biosynthesis of sucrose, contains a domain which exhibits considerable similarity to SPP albeit without conservation of the catalytic residues. The catalytic machinery of the synthase resides in another domain. It seems likely that the phosphatase-like domain is involved in substrate binding, possibly binding both substrates in a "product-like" orientation prior to ligation by the synthase catalytic domain. |
| References | RN [1] RM PMID: 11050182 RT Purification, molecular cloning, and sequence analysis of sucrose-6F-phosphate phosphohydrolase from plants. RA Lunn JE, Ashton AR, Hatch MD, Heldt HW. RL Proc Natl Acad Sci U S A 2000 Nov 7;97(23):12914-9 |