| Accession | TIGR01475 |
| Name | ubiA_other |
| Function | putative 4-hydroxybenzoate polyprenyltransferase |
| Trusted Cutoff | 180.80 |
| Domain Trusted Cutoff | 180.80 |
| Noise Cutoff | 148.10 |
| Domain Noise Cutoff | 148.10 |
| Isology Type | hypoth_equivalog |
| EC Number | 2.5.1.- |
| HMM Length | 282 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Menaquinone and ubiquinone |
| Gene Ontology Term | GO:0006744: ubiquinone biosynthetic process biological_process |
| | GO:0008412: 4-hydroxybenzoate octaprenyltransferase activity molecular_function |
| Author | Haft DH |
| Entry Date | Mar 20 2002 2:40PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | A fairly deep split separates this polyprenyltransferase subfamily from the set of mitochondrial and proteobacterial 4-hydroxybenzoate polyprenyltransferases, described in TIGR01474. Protoheme IX farnesyltransferase (heme O synthase) (TIGR01473) is more distantly related. Because no species appears to have both this protein and a member of TIGR01474, it is likely that this HMM represents 4-hydroxybenzoate polyprenyltransferase, a critical enzyme of ubiquinone biosynthesis, in the Archaea, Gram-positive bacteria, Aquifex aeolicus, the Chlamydias, etc. |
| Genome Property | GenProp0136: ubiquinone biosynthesis from chorismate, aerobic (HMM) |
| | GenProp0829: menaquinone biosynthesis via futalosine (HMM) |
