HMM Summary Page: TIGR01473

Functionprotoheme IX farnesyltransferase
Gene SymbolcyoE
Trusted Cutoff210.30
Domain Trusted Cutoff210.30
Noise Cutoff138.30
Domain Noise Cutoff138.30
Isology Typeequivalog
EC Number2.5.1.-
HMM Length281
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryHeme, porphyrin, and cobalamin
Gene Ontology TermGO:0006783: heme biosynthetic process biological_process
GO:0008495: protoheme IX farnesyltransferase activity molecular_function
AuthorHaft DH
Entry DateMar 20 2002 10:02AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes protoheme IX farnesyltransferase, also called heme O synthase, an enzyme that creates an intermediate in the biosynthesis of heme A. Prior to the description of its enzymatic function, this protein was often called a cytochrome o ubiquinol oxidase assembly factor.
ReferencesDR EXPERIMENTAL; SP:P24009; Bacillus subtilis; CtaB DR EXPERIMENTAL; EGAD|109348; Bacillus subtilis; CtaO DR EXPERIMENTAL; SP:P18404; Escherichia coli; CyoE DR EXPERIMENTAL; SP:P21592; Saccharomyces cerevisiae; COX10 DR EXPERIMENTAL; PIR:I38603; Homo sapiens RN [1] RM 9378722 RN [2] RM 93129216 RN [3] RM 8118433 DR HAMAP; MF_00154; 433 of 455
Genome PropertyGenProp0618: cytochrome (quinone) oxidase, bo type (HMM)
GenProp0614: cytochrome c oxidase, mitochondrial, caa3-type (HMM)