HMM Summary Page: TIGR01465

Functionprecorrin-4 C11-methyltransferase
Gene SymbolcobM
Trusted Cutoff259.65
Domain Trusted Cutoff259.65
Noise Cutoff206.85
Domain Noise Cutoff206.85
Isology Typeequivalog
EC Number2.1.1.133
HMM Length247
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryHeme, porphyrin, and cobalamin
Gene Ontology TermGO:0005737: cytoplasm cellular_component
GO:0009236: cobalamin biosynthetic process biological_process
GO:0046026: precorrin-4 C11-methyltransferase activity molecular_function
AuthorHaft DH
Entry DateMar 12 2002 2:33PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents precorrin-4 C11-methyltransferase, one of two methyltransferases commonly referred to as precorrin-3 methylase (the other is precorrin-3B C17-methyltransferase, EC This enzyme participates in the pathway toward the biosynthesis of cobalamin and related products.
Genome PropertyGenProp0113: cobyrinic acid diamide biosynthesis, aerobic pathway (HMM)
GenProp0275: cobyrinic acid diamide biosynthesis, anaerobic pathway (HMM)