| Accession | TIGR01464 |
| Name | hemE |
| Function | uroporphyrinogen decarboxylase |
| Gene Symbol | hemE |
| Trusted Cutoff | 302.95 |
| Domain Trusted Cutoff | 302.95 |
| Noise Cutoff | 140.60 |
| Domain Noise Cutoff | 140.60 |
| Isology Type | equivalog |
| EC Number | 4.1.1.37 |
| HMM Length | 338 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Heme, porphyrin, and cobalamin |
| Gene Ontology Term | GO:0004853: uroporphyrinogen decarboxylase activity molecular_function |
| | GO:0006779: porphyrin-containing compound biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Mar 12 2002 8:39AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents uroporphyrinogen decarboxylase (HemE), which converts uroporphyrinogen III to coproporphyrinogen III. This step takes the pathway toward protoporphyrin IX, a common precursor of both heme and chlorophyll, rather than toward precorrin 2 and its products. |
| References |
DR HAMAP; MF_00218; 370 of 374 |
| Genome Property | GenProp0221: protoporphyrin IX biosynthesis from uroporphyrinogen III (HMM) |
