HMM Summary Page: TIGR01463
Accession | TIGR01463 |
Name | mtaA_cmuA |
Function | methyltransferase, MtaA/CmuA family |
Trusted Cutoff | 235.40 |
Domain Trusted Cutoff | 235.40 |
Noise Cutoff | 103.65 |
Domain Noise Cutoff | 103.65 |
Isology Type | subfamily |
EC Number | 2.1.1.- |
HMM Length | 340 |
Author | Haft DH |
Entry Date | Mar 11 2002 5:13PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This subfamily is closely related to, yet is distinct from, uroporphyrinogen decarboxylase (EC 4.1.1.37). It includes two isozymes from Methanosarcina barkeri of methylcobalamin--coenzyme M methyltransferase. It also includes a chloromethane utilization protein, CmuA, which transfers the methyl group of chloromethane to a corrinoid protein. |
References | RN [1] RM 11133460 RT Chloromethane utilization gene cluster from Hyphomicrobium chloromethanicum strain CM2(T) and development of functional gene probes to detect halomethane-degrading bacteria. RA McAnulla C, Woodall CA, McDonald IR, Studer A, Vuilleumier S, Leisinger T, Murrell JC. RL Appl Environ Microbiol 2001 Jan;67(1):307-16 RN [2] RM 8654414 RT Methylcobalamin: coenzyme M methyltransferase isoenzymes MtaA and MtbA from Methanosarcina barkeri. Cloning, sequencing and differential transcription of the encoding genes, and functional overexpression of the mtaA gene in Escherichia coli. RA Harms U, Thauer RK. RL Eur J Biochem 1996 Feb 1;235(3):653-9 |