HMM Summary Page: TIGR01462

Functiontranscription elongation factor GreA
Gene SymbolgreA
Trusted Cutoff139.00
Domain Trusted Cutoff139.00
Noise Cutoff130.65
Domain Noise Cutoff130.65
Isology Typesubfamily_domain
HMM Length151
Mainrole CategoryTranscription
Subrole CategoryTranscription factors
Gene Ontology TermGO:0003711: transcription elongation regulator activity molecular_function
GO:0006354: transcription elongation, DNA-dependent biological_process
AuthorHaft DH
Entry DateMar 7 2002 2:13PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe GreA and GreB transcription elongation factors enable to continuation of RNA transcription past template-encoded arresting sites. Among the Proteobacteria, distinct clades of GreA and GreB are found. GreA differs functionally in that it releases smaller oligonucleotides. Because members of the family outside the Proteobacteria resemble GreA more closely than GreB, the GreB clade (TIGR01461) forms a plausible outgroup and the remainder of the GreA/B family, included in this model, is designated GreA. In the Chlamydias and some spirochetes, the region described by this HMM is found as the C-terminal region of a much larger protein.
References DR HAMAP; MF_00105; 206 of 229