| Accession | TIGR01455 |
| Name | glmM |
| Function | phosphoglucosamine mutase |
| Gene Symbol | glmM |
| Trusted Cutoff | 447.55 |
| Domain Trusted Cutoff | 447.55 |
| Noise Cutoff | 339.25 |
| Domain Noise Cutoff | 339.25 |
| Isology Type | equivalog |
| EC Number | 5.4.2.10 |
| HMM Length | 442 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Gene Ontology Term | GO:0008966: phosphoglucosamine mutase activity molecular_function |
| | GO:0009103: lipopolysaccharide biosynthetic process biological_process |
| | GO:0009252: peptidoglycan biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Mar 1 2002 10:31AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM describes GlmM, phosphoglucosamine mutase, also designated in MrsA and YhbF E. coli, UreC in Helicobacter pylori, and femR315 or FemD in Staphlococcus aureus. It converts glucosamine-6-phosphate to glucosamine-1-phosphate as part of the pathway toward UDP-N-acetylglucosamine for peptidoglycan and lipopolysaccharides. |
| References | DR EXPERIMENTAL; OMNI|SA2151; Staphylococcus aureus
DR EXPERIMENTAL; SP:P25177; Helicobacter pylori
DR EXPERIMENTAL; PIR:I41215; Escherichia coli
RN [1]
RM 8550580
RT Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli.
RA Mengin-Lecreulx D, van Heijenoort J.
RL J Biol Chem 1996 Jan 5;271(1):32-9
RN [2]
RM 9171391
RT The Helicobacter pylori ureC gene codes for a phosphoglucosamine mutase.
RA De Reuse H, Labigne A, Mengin-Lecreulx D.
RL J Bacteriol 1997 Jun;179(11):3488-93
RN [3]
RM 9286983
RT The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase.
RA Jolly L, Wu S, van Heijenoort J, de Lencastre H, Mengin-Lecreulx D, Tomasz A.
RL J Bacteriol 1997 Sep;179(17):5321-5
DR HAMAP; MF_01554; 469 of 502 |
| Genome Property | GenProp0750: UDP-N-acetylglucosamine biosynthesis from fructose-6-phosphate (HMM) |
