HMM Summary Page: TIGR01453

Functiongroup I intron endonuclease
Trusted Cutoff56.05
Domain Trusted Cutoff56.05
Noise Cutoff44.80
Domain Noise Cutoff44.80
Isology Typesubfamily
HMM Length215
Gene Ontology TermGO:0004519: endonuclease activity molecular_function
GO:0006316: movement of group I intron biological_process
AuthorHaft DH
Entry DateFeb 28 2002 3:32PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents one subfamily of endonucleases containing the endo/excinuclease amino terminal domain, Pfam:PF01541 at its amino end. A distinct subfamily includes excinuclease abc subunit c (uvrC). Members of PF01541 are often termed GIY-YIG endonucleases after conserved motifs near the amino end. This subfamily in this HMM is found in open reading frames of group I introns in both phage and mitochondria. The closely related endonucleases of phage T4: segA, segB, segC, segD and segE, score below the trusted cutoff for the family.