| Accession | TIGR01433 |
| Name | CyoA |
| Function | ubiquinol oxidase, subunit II |
| Gene Symbol | cyoA |
| Trusted Cutoff | 266.20 |
| Domain Trusted Cutoff | 266.20 |
| Noise Cutoff | 218.75 |
| Domain Noise Cutoff | 218.75 |
| Isology Type | equivalog |
| EC Number | 1.10.3.- |
| HMM Length | 226 |
| Mainrole Category | Energy metabolism |
| Subrole Category | Electron transport |
| Gene Ontology Term | GO:0008827: cytochrome o ubiquinol oxidase activity molecular_function |
| | GO:0015990: electron transport coupled proton transport biological_process |
| | GO:0016021: integral to membrane cellular_component |
| Author | Selengut J |
| Entry Date | Feb 4 2002 11:54AM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme catalyzes the oxidation of ubiquinol with the concomitant reduction of molecular oxygen to water. This acts as the terminal electron acceptor in the respiratory chain. Subunit II is responsible for binding and oxidation of the ubiquinone substrate. This sequence is closely related to QoxA, which oxidizes quinol in gram positive bacteria but which is in complex with subunits which utilize cytochromes a in the reduction of molecular oxygen. Slightly more distantly related is subunit II of cytochrome c oxidase which uses cyt. c as the oxidant. |
| References | RN [1]
RM 2162835
RT The sequence of the cyo operon indicates substantial structural similarities between the cytochrome o ubiquinol oxidase of Escherichia coli and the aa3-type family of cytochrome c oxidases
RA Chepuri V, Lemieux L, Au DC, Gennis RB
RL J Biol Chem 1990 Jul 5;265(19):11185-92
DR EXPERIMENTAL; EGAD|20044; Escherichia coli CyoA
DR OUTGROUP; SP|P34957; Bacillus subtilis QoxA |
| Genome Property | GenProp0618: cytochrome (quinone) oxidase, bo type (HMM) |
