| Accession | TIGR01420 |
| Name | pilT_fam |
| Function | twitching motility protein |
| Trusted Cutoff | 319.10 |
| Domain Trusted Cutoff | 319.10 |
| Noise Cutoff | 220.05 |
| Domain Noise Cutoff | 220.05 |
| Isology Type | subfamily |
| HMM Length | 343 |
| Mainrole Category | Cell envelope |
| Subrole Category | Surface structures |
| Gene Ontology Term | GO:0005524: ATP binding molecular_function |
| | GO:0043107: type IV pilus-dependent motility biological_process |
| Author | Haft DH |
| Entry Date | Jan 22 2002 1:35PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. |
| References | RM 10993081
RT Pilus retraction powers bacterial twitching motility.
RA Merz AJ, So M, Sheetz MP.
RL Nature 2000 Sep 7;407(6800):98-102 |
