HMM Summary Page: TIGR01415

Functionpyridoxal-phosphate dependent TrpB-like enzyme
Trusted Cutoff518.85
Domain Trusted Cutoff518.85
Noise Cutoff295.15
Domain Noise Cutoff295.15
Isology Typehypoth_equivalog
HMM Length419
Mainrole CategoryUnknown function
Subrole CategoryEnzymes of unknown specificity
AuthorHaft DH
Entry DateJan 9 2002 4:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents a family of pyridoxal-phosphate dependent enzyme (PF00291) closely related to the beta subunit of tryptophan synthase (TIGR00263). However, the only case in which a member of this family replaces a member of TIGR00263 is in Sulfolobus species which contain two sequences which hit this model, one of which is proximal to the alpha subunit. In every other case so far, either the species appears not to make tryptophan (there is no trp synthase alpha subunit), or a trp synthase beta subunit matching TIGR00263 is also found.
References DR HAMAP; MF_00133; 20 of 315
Genome PropertyGenProp0037: tryptophan biosynthesis from ribose-5-phosphate (HMM)