HMM Summary Page: TIGR01406

FunctionDNA polymerase III, epsilon subunit
Gene SymboldnaQ
Trusted Cutoff222.70
Domain Trusted Cutoff222.70
Noise Cutoff113.60
Domain Noise Cutoff113.60
Isology Typeequivalog
EC Number2.7.7.7
HMM Length231
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0003887: DNA-directed DNA polymerase activity molecular_function
GO:0004527: exonuclease activity molecular_function
GO:0006260: DNA replication biological_process
GO:0009360: DNA polymerase III complex cellular_component
AuthorHaft DH
Entry DateDec 21 2001 10:37AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model represents DnaQ, the DNA polymerase III epsilon subunit, as found in most Proteobacteria. It consists largely of an exonuclease domain as described in Pfam HMM PF00929. In Gram-positive bacteria, closely related regions are found both in the Gram-positive type DNA polymerase III alpha subunit and as an additional N-terminal domain of a DinG-family helicase. Both are excluded from this model, as are smaller proteins, also outside the Proteobacteria, that are similar in size to the epsilon subunit but as different in sequence as are the epsilon-like regions found in Gram-positive bacteria.
Genome PropertyGenProp0263: DNA polymerase III, bacterial (HMM)