HMM Summary Page: TIGR01394

FunctionGTP-binding protein TypA/BipA
Gene SymboltypA
Trusted Cutoff757.30
Domain Trusted Cutoff757.30
Noise Cutoff262.60
Domain Noise Cutoff262.60
Isology Typeequivalog
HMM Length594
Mainrole CategoryRegulatory functions
Subrole CategoryOther
Gene Ontology TermGO:0005525: GTP binding molecular_function
GO:0006412: translation biological_process
GO:0006950: response to stress biological_process
AuthorHaft DH
Entry DateDec 11 2001 5:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis bacterial (and Arabidopsis) protein, termed TypA or BipA, a GTP-binding protein, is phosphorylated on a tyrosine residue under some cellular conditions. Mutants show altered regulation of some pathways, but the precise function is unknown.
ReferencesRN [1] RM PMID: 15297874 RT A dedicated translation factor controls the synthesis of the global regulator Fis. RA Owens RM, Pritchard G, Skipp P, Hodey M, Connell SR, Nierhaus KH, O'Connor CD RL EMBO J. 2004 Aug 18;23(16):3375-85. Epub 2004 Aug 5. RN [2] RM PMID: 9622352 RT BipA: a tyrosine-phosphorylated GTPase that mediates interactions between enteropathogenic Escherichia coli (EPEC) and epithelial cells. RA Farris,M., Grant,A., Richardson,T.B. and O'Connor,C.D. RL Mol. Microbiol. 28 (2), 265-279 (1998)