HMM Summary Page: TIGR01388

Functionribonuclease D
Gene Symbolrnd
Trusted Cutoff298.95
Domain Trusted Cutoff298.95
Noise Cutoff138.75
Domain Noise Cutoff138.75
Isology Typeequivalog
EC Number3.1.13.5
HMM Length363
Mainrole CategoryTranscription
Subrole CategoryRNA processing
Gene Ontology TermGO:0006396: RNA processing biological_process
GO:0016891: endoribonuclease activity, producing 5'-phosphomonoesters molecular_function
AuthorHaft DH
Entry DateDec 3 2001 11:20AM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model describes ribonuclease D, a 3'-exonuclease shown to act on tRNA both in vitro and when overexpressed in vivo. Trusted members of this family are restricted to the Proteobacteria; Aquifex, Mycobacterial, and eukaryotic homologs are not full-length homologs. Ribonuclease D is not essential in E. coli and is deleterious when overexpressed. Its precise biological role is still unknown.