HMM Summary Page: TIGR01387

Functionheavy metal response regulator
Trusted Cutoff279.20
Domain Trusted Cutoff279.20
Noise Cutoff266.00
Domain Noise Cutoff266.00
Isology Typesubfamily
HMM Length218
AuthorHaft DH
Entry DateNov 28 2001 5:53PM
Last ModifiedFeb 14 2011 3:27PM
CommentMembers of this family contain a response regulator receiver domain (Pfam:PF00072) and an associated transcriptional regulatory region (Pfam:PF00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system.