HMM Summary Page: TIGR01376

Functionchlamydial polymorphic outer membrane protein repeat
Trusted Cutoff15.00
Domain Trusted Cutoff15.00
Noise Cutoff12.10
Domain Noise Cutoff12.10
Isology Typerepeat
HMM Length28
AuthorHaft DH
Entry DateNov 7 2001 5:53PM
Last ModifiedMar 1 2011 11:50AM
CommentThis HMM represents a repeat region of about 27 residues that appears from twice to over twenty times in Chlamydial polymorphic outer membrane proteins (POMP). Characteristic motifs in the repeat are FXXN and GGAI. Except for a few apparently truncated examples, Chlamydial proteins have this repeat region if and only if they also have the autotransporter beta-domain (PF03797) at the C-terminus, with Phe as the C-terminal residue. This repeat is observed, but is very rare, outside the Chlamydias.
ReferencesRM 10587946 RT Computational analysis of the polymorphic membrane protein superfamily of Chlamydia trachomatis and Chlamydia pneumoniae. RA Grimwood J, Stephens RS. RL Microb Comp Genomics 1999;4(3):187-201 DR PFAM; PF02415