HMM Summary Page: TIGR01375

Functionsarcosine oxidase, gamma subunit family
Gene SymbolsoxG
Trusted Cutoff143.95
Domain Trusted Cutoff143.95
Noise Cutoff29.55
Domain Noise Cutoff29.55
Isology Typesubfamily
EC Number1.5.3.1
HMM Length152
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
AuthorDodson RJ
Entry DateNov 2 2001 4:16PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes the gamma subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. The gamma subunit is the most divergent between operons of the four subunits. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms.