HMM Summary Page: TIGR01374

Functionsarcosine oxidase, delta subunit family
Trusted Cutoff116.50
Domain Trusted Cutoff116.50
Noise Cutoff40.75
Domain Noise Cutoff40.75
Isology Typesubfamily
HMM Length83
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
AuthorDodson RJ
Entry DateNov 2 2001 4:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes the delta subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) form