HMM Summary Page: TIGR01355

Functioncytidine deaminase
Gene Symbolcdd
Trusted Cutoff275.00
Domain Trusted Cutoff275.00
Noise Cutoff90.25
Domain Noise Cutoff90.25
Isology Typeequivalog
EC Number3.5.4.5
HMM Length283
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategorySalvage of nucleosides and nucleotides
Gene Ontology TermGO:0004126: cytidine deaminase activity molecular_function
GO:0008655: pyrimidine-containing compound salvage biological_process
AuthorHaft DH
Entry DateOct 4 2001 4:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis homodimeric zinc metalloprotein is found in Arabidopis and some Proteobacteria. A related, homotetrameric form with a much smaller subunit is found most bacteria and in animals. Both types may act on deoxycytidine as well as cytidine.
ReferencesRM 10493793 RT Cytidine deaminases from B. subtilis and E. coli: compensating effects of changing zinc coordination and quaternary structure. RA Carlow DC, Carter CW Jr, Mejlhede N, Neuhard J, Wolfenden R. RL Biochemistry 1999 Sep 21;38(38):12258-65 DR HAMAP; MF_01558; 49 of 71