HMM Summary Page: TIGR01354

Functioncytidine deaminase
Gene Symbolcdd
Trusted Cutoff113.65
Domain Trusted Cutoff113.65
Noise Cutoff70.95
Domain Noise Cutoff70.95
Isology Typeequivalog
EC Number3.5.4.5
HMM Length126
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategorySalvage of nucleosides and nucleotides
Gene Ontology TermGO:0004126: cytidine deaminase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0008655: pyrimidine-containing compound salvage biological_process
AuthorHaft DH
Entry DateOct 4 2001 3:34PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis small, homotetrameric zinc metalloprotein is found in humans and most bacteria. A related, homodimeric form with a much larger subunit is found in E. coli and in Arabidopsis. Both types may act on deoxycytidine as well as cytidine.
ReferencesRM 10493793 RT Cytidine deaminases from B. subtilis and E. coli: compensating effects of changing zinc coordination and quaternary structure. RA Carlow DC, Carter CW Jr, Mejlhede N, Neuhard J, Wolfenden R. RL Biochemistry 1999 Sep 21;38(38):12258-65