HMM Summary Page: TIGR01351

Functionadenylate kinase
Trusted Cutoff168.00
Domain Trusted Cutoff168.00
Noise Cutoff157.10
Domain Noise Cutoff157.10
Isology Typesubfamily
EC Number2.7.4.-
HMM Length212
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole CategoryNucleotide and nucleoside interconversions
AuthorDeBoy RT, Haft DH
Entry DateSep 28 2001 3:37PM
Last ModifiedFeb 21 2012 12:20PM
CommentAdenylate kinase (EC converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason.
ReferencesDR HAMAP; MF_00235; 444 of 487