| Accession | TIGR01344 |
| Name | malate_syn_A |
| Function | malate synthase A |
| Gene Symbol | aceB |
| Trusted Cutoff | 594.50 |
| Domain Trusted Cutoff | 594.50 |
| Noise Cutoff | 122.10 |
| Domain Noise Cutoff | 122.10 |
| Isology Type | equivalog |
| EC Number | 2.3.3.9 |
| HMM Length | 511 |
| Mainrole Category | Energy metabolism |
| Subrole Category | TCA cycle |
| Gene Ontology Term | GO:0004474: malate synthase activity molecular_function |
| | GO:0006099: tricarboxylic acid cycle biological_process |
| Author | Haft DH |
| Entry Date | Sep 19 2001 3:52PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents plant malate synthase and one of two bacterial forms, designated malate synthase A. The distantly related malate synthase G is described by a separate model. This enzyme and isocitrate lyase are the two characteristic enzymes of the glyoxylate shunt. The shunt enables the cell to use acetyl-CoA to generate increased levels of TCA cycle intermediates for biosynthetic pathways such as gluconeogenesis. |
| References | DR PFAM; PF01274; Malate synthase |
| Genome Property | GenProp0023: glyoxylate shunt (HMM) |
