HMM Summary Page: TIGR01331

Function3'(2'),5'-bisphosphate nucleotidase
Gene SymbolcysQ
Trusted Cutoff228.80
Domain Trusted Cutoff228.80
Noise Cutoff145.00
Domain Noise Cutoff145.00
Isology Typeequivalog
EC Number3.1.3.7
HMM Length250
Mainrole CategoryCentral intermediary metabolism
Subrole CategorySulfur metabolism
Gene Ontology TermGO:0006790: sulfur compound metabolic process biological_process
GO:0008441: 3'(2'),5'-bisphosphate nucleotidase activity molecular_function
AuthorHaft DH
Entry DateAug 24 2001 5:32PM
Last ModifiedFeb 14 2011 3:27PM
CommentSulfate is incorporated into 3-phosphoadenylylsulfate, PAPS, for utilization in pathways such as methionine biosynthesis. Transfer of sulfate from PAPS to an acceptor leaves adenosine 3'-5'-bisphosphate, APS. This HMM describes a form found in bacteria of the enzyme 3'(2'),5'-bisphosphate nucleotidase, which removes the 3'-phosphate from APS to regenerate AMP and help drive the cycle.