HMM Summary Page: TIGR01330

Function3'(2'),5'-bisphosphate nucleotidase
Trusted Cutoff267.05
Domain Trusted Cutoff267.05
Noise Cutoff152.45
Domain Noise Cutoff152.45
Isology Typeequivalog
EC Number3.1.3.7
HMM Length359
Gene Ontology TermGO:0006790: sulfur compound metabolic process biological_process
GO:0008441: 3'(2'),5'-bisphosphate nucleotidase activity molecular_function
AuthorHaft DH
Entry DateAug 24 2001 4:12PM
Last ModifiedFeb 14 2011 3:27PM
CommentSulfate is incorporated into 3-phosphoadenylylsulfate, PAPS, for utilization in pathways such as methionine biosynthesis. Transfer of sulfate from PAPS to an acceptor leaves adenosine 3'-5'-bisphosphate, APS. This HMM describes a form found in plants of the enzyme 3'(2'),5'-bisphosphate nucleotidase, which removes the 3'-phosphate from APS to regenerate AMP and help drive the cycle. Sensitivity of this essential enzyme to sodium and other metal ions results is responsible for characterization of this enzyme as a salt tolerance protein. Some members of this family are active also as inositol 1-monophosphatase.
ReferencesRM 10205895 RT The Arabidopsis HAL2-like gene family includes a novel sodium-sensitive phosphatase. RA Gil-Mascarell R, Lopez-Coronado JM, Belles JM, Serrano R, Rodriguez PL RL Plant J 1999 Feb;17(4):373-83