HMM Summary Page: TIGR01326

FunctionO-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
Trusted Cutoff495.10
Domain Trusted Cutoff495.10
Noise Cutoff483.05
Domain Noise Cutoff483.05
Isology Typesubfamily
HMM Length418
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAspartate family
Gene Ontology TermGO:0003961: O-acetylhomoserine aminocarboxypropyltransferase activity molecular_function
GO:0004124: cysteine synthase activity molecular_function
GO:0009086: methionine biosynthetic process biological_process
GO:0016765: transferase activity, transferring alkyl or aryl (other than methyl) groups molecular_function
GO:0019344: cysteine biosynthetic process biological_process
GO:0019413: acetate biosynthetic process biological_process
AuthorHaft DH
Entry DateAug 23 2001 12:51PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC and O-acetylserine (OAS) sulphydrylase (EC An alternate name for OAH sulfhydrylase is homocysteine synthase. This HMM is designated subfamily because it may or may not have both activities.
ReferencesDR PROSITE; PDOC00677; Cys/Met metabolism enzymes pyridoxal-phosphate attachment site
Genome PropertyGenProp0161: methionine biosynthesis from homoserine (HMM)