HMM Summary Page: TIGR01317

Functionglutamate synthase, NADH/NADPH, small subunit
Gene SymbolgltD
Trusted Cutoff447.70
Domain Trusted Cutoff447.70
Noise Cutoff370.15
Domain Noise Cutoff370.15
Isology Typesubfamily_domain
EC Number1.4.1.-
HMM Length485
Gene Ontology TermGO:0006537: glutamate biosynthetic process biological_process
GO:0009342: glutamate synthase complex (NADPH) cellular_component
GO:0045181: glutamate synthase activity, NADH or NADPH as acceptor molecular_function
AuthorHaft DH
Entry DateAug 1 2001 1:42PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM represents one of three built for the NADPH-dependent or NADH-dependent glutamate synthase (EC and, respectively) small subunit or homologous region. TIGR01316 describes a family in several archaeal and deeply branched bacterial lineages of a homotetrameric form for which there is no large subunit. Another model describes glutamate synthase small subunit from gamma and some alpha subdivision Proteobacteria plus paralogs of unknown function. This model describes the small subunit, or homologous region of longer forms proteins, of eukaryotes, Gram-positive bacteria, cyanobacteria, and some other lineages. All members with known function participate in NADH or NADPH-dependent reactions to interconvert between glutamine plus 2-oxoglutarate and two molecules of glutamate.