HMM Summary Page: TIGR01276

Functionthiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein
Gene SymbolthiB
Trusted Cutoff317.15
Domain Trusted Cutoff317.15
Noise Cutoff268.75
Domain Noise Cutoff268.75
Isology Typeequivalog
HMM Length324
Mainrole CategoryTransport and binding proteins
Subrole CategoryOther
Gene Ontology TermGO:0009897: external side of plasma membrane cellular_component
GO:0015619: thiamine pyrophosphate-transporting ATPase activity molecular_function
GO:0015888: thiamine transport biological_process
GO:0030288: outer membrane-bounded periplasmic space cellular_component
GO:0030974: thiamine pyrophosphate transport biological_process
GO:0030975: thiamine binding molecular_function
GO:0030976: thiamine pyrophosphate binding molecular_function
GO:0048502: thiamine-transporting ATPase activity molecular_function
GO:0055052: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing cellular_component
AuthorHaft DH
Entry DateJun 20 2001 3:22PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis model finds the thiamine (and thiamine pyrophosphate) ABC transporter periplasmic binding protein ThiB in proteobacteria. Completed genomes having this protein (E. coli, Vibrio cholera, Haemophilus influenzae) also have the permease ThiP, described by TIGRFAMs equivalog model TIGR01253.
ReferencesRM 98204886 RT thiBPQ encodes an ABC transporter required for transport of thiamine and thiamine pyrophosphate in Salmonella typhimurium. RA Webb E, Claas K, Downs D. RL J Biol Chem 1998 Apr 10;273(15):8946-50
Genome PropertyGenProp0252: thiamine/TPP ABC transporter ThiBPQ (HMM)