HMM Summary Page: TIGR01270

Functiontryptophan 5-monooxygenase
Trusted Cutoff705.50
Domain Trusted Cutoff705.50
Noise Cutoff608.15
Domain Noise Cutoff608.15
Isology Typeequivalog
EC Number1.14.16.4
HMM Length464
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0004510: tryptophan 5-monooxygenase activity molecular_function
GO:0006568: tryptophan metabolic process biological_process
AuthorHaft DH
Entry DateJun 5 2001 3:37PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes tryptophan 5-monooxygenase, a member of the family of tetrameric, biopterin-dependent aromatic amino acid hydroxylases found in metazoans. It is closely related to tetrameric phenylalanine-4-hydroxylase and tyrosine 3-monooxygenase, and more distantly related to the monomeric phenylalanine-4-hydroxylase found in some Gram-negative bacteria.