| Accession | TIGR01251 |
| Name | ribP_PPkin |
| Function | ribose-phosphate diphosphokinase |
| Gene Symbol | prs |
| Trusted Cutoff | 113.00 |
| Domain Trusted Cutoff | 113.00 |
| Noise Cutoff | 107.35 |
| Domain Noise Cutoff | 107.35 |
| Isology Type | subfamily |
| EC Number | 2.7.6.1 |
| HMM Length | 309 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Purine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0004749: ribose phosphate diphosphokinase activity molecular_function |
| | GO:0009152: purine ribonucleotide biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | May 17 2001 4:16PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Alternate name: phosphoribosylpyrophosphate synthetase
In some systems, close homologs lacking enzymatic activity exist and perform regulatory functions. The model is designated subfamily rather than equivalog for this reason. |
| References | RN [1]
RM 8132556
RT A novel 39-kDa phosphoribosylpyrophosphate synthetase-associated protein of rat liver. Cloning, high sequence similarity to the catalytic subunits, and a negative regulatory role.
RA Kita K, Ishizuka T, Ishijima S, Sonoda T, Tatibana M.
RL J Biol Chem 1994 Mar 18;269(11):8334-40
DR HAMAP; MF_00583; 155 of 155 |
| Genome Property | GenProp0109: histidine biosynthesis from ribose-5-phosphate (HMM) |
| | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
| | GenProp0037: tryptophan biosynthesis from ribose-5-phosphate (HMM) |
| | GenProp0187: pyrimidine (uridine-5'-phosphate) de novo biosynthesis (HMM) |
| | GenProp0800: bacterial core gene set, 1 or more per genome (HMM) |
