HMM Summary Page: TIGR01237

Functionputative delta-1-pyrroline-5-carboxylate dehydrogenase
Gene SymbolpruA
Trusted Cutoff659.65
Domain Trusted Cutoff659.65
Noise Cutoff443.00
Domain Noise Cutoff443.00
Isology Typeequivalog
EC Number1.2.1.88
HMM Length511
Mainrole CategoryEnergy metabolism
Subrole CategoryAmino acids and amines
Gene Ontology TermGO:0003842: 1-pyrroline-5-carboxylate dehydrogenase activity molecular_function
GO:0006562: proline catabolic process biological_process
AuthorHaft DH, Dodson RJ
Entry DateMay 10 2001 1:55PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme is the second of two in the degradation of proline to glutamate. This model represents one of several related branches of delta-1-pyrroline-5-carboxylate dehydrogenase. Members of this branch may be associated with proline dehydrogenase (the other enzyme of the pathway from proline to glutamate) but have not been demonstrated experimentally. The branches are not as closely related to each other as some distinct aldehyde dehydrogenases are to some; separate models were built to let each model describe a set of equivalogs.
ReferencesDR HAMAP; MF_00733; 34 of 34