HMM Summary Page: TIGR01213

FunctiontRNA pseudouridine(54/55) synthase
Trusted Cutoff239.55
Domain Trusted Cutoff239.55
Noise Cutoff81.20
Domain Noise Cutoff81.20
Isology Typeequivalog
EC Number5.4.99.25
HMM Length387
Mainrole CategoryHypothetical proteins
Subrole CategoryConserved
AuthorHaft DH
Entry DateApr 4 2001 9:25AM
Last ModifiedDec 21 2011 12:42PM
CommentMembers of this family show twilight-zone similarity to several predicted RNA pseudouridine synthases. All trusted members of this family are archaeal. Several eukaryotic homologs lack N-terminal homology including two CXXC motifs.
ReferencesDR COGS; COG1258 RN [1] RM PMID:21628430 RT Pseudouridine formation in archaeal RNAs: The case of Haloferax volcanii. RA Blaby IK, Majumder M, Chatterjee K, Jana S, Grosjean H, de Crecy-Lagard V, Gupta R RL RNA. 2011 Jul;17(7):1367-80.