| Accession | TIGR01209 |
| Name | TIGR01209 |
| Function | RNA ligase, Pab1020 family |
| Trusted Cutoff | 136.90 |
| Domain Trusted Cutoff | 136.90 |
| Noise Cutoff | 136.60 |
| Domain Noise Cutoff | 136.60 |
| Isology Type | hypoth_equivalog |
| HMM Length | 375 |
| Mainrole Category | Transcription |
| Subrole Category | RNA processing |
| Gene Ontology Term | GO:0005737: cytoplasm cellular_component |
| | GO:0008452: RNA ligase activity molecular_function |
| | GO:0016070: RNA metabolic process biological_process |
| Author | Haft DH |
| Entry Date | Mar 26 2001 4:15PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are found, so far, in a single copy per genome and largely in thermophiles, of which only Aquifex aeolicus is bacterial rather than archaeal. PSI-BLAST converges after a single iteration to the whole of this family and reveals no convincing similarity to any other protein. The member protein Pab1020 has been characterized as an RNA ligase with circularization activity. |
| References | RN [1]
RM PMID:18511537
RT The structure of an archaeal homodimeric ligase which has RNA circularization activity.
RA Brooks MA, Meslet-Cladiere L, Graille M, Kuhn J, Blondeau K, Myllykallio H, van Tilbeurgh H
RL Protein Sci. 2008 Aug;17(8):1336-45. Epub 2008 May 29.
DR COGS; COG1423 |
| Genome Property | GenProp0898: RNA ligase/unknown protein pair (HMM) |
