| Accession | TIGR01208 |
| Name | rmlA_long |
| Function | glucose-1-phosphate thymidylyltransferase |
| Trusted Cutoff | 320.25 |
| Domain Trusted Cutoff | 320.25 |
| Noise Cutoff | 196.85 |
| Domain Noise Cutoff | 196.85 |
| Isology Type | equivalog |
| EC Number | 2.7.7.24 |
| HMM Length | 353 |
| Gene Ontology Term | GO:0000271: polysaccharide biosynthetic process biological_process |
| | GO:0008879: glucose-1-phosphate thymidylyltransferase activity molecular_function |
| Author | Haft DH |
| Entry Date | Mar 21 2001 3:24PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The family of known and putative glucose-1-phosphate thymidyltransferase (also called dTDP-glucose synthase) shows a deep split into a short form (see TIGR01207) and a long form described by this model. The homotetrameric short form is found in numerous bacterial species that incorporate dTDP-L-rhamnose, which it helps synthesize, into the cell wall. It is subject to feedback inhibition. This form, in contrast, is found in many species for which it serves as a sugar-activating enzyme for antibiotic biosynthesis and or other, unknown pathways, and in which dTDP-L-rhamnose is not necessarily produced.
Alternate name: dTDP-D-glucose synthase |
| References | DR COGS; COG1209 |
| Genome Property | GenProp0950: 4,6-dideoxy-4-oxo-dTDP-D-glucose biosynthesis from glucose-1-phosphate (HMM) |
