HMM Summary Page: TIGR01206

Functionlysine biosynthesis protein LysW
Gene SymbollysW
Trusted Cutoff53.20
Domain Trusted Cutoff53.20
Noise Cutoff24.55
Domain Noise Cutoff24.55
Isology Typeequivalog
HMM Length54
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryAspartate family
Gene Ontology TermGO:0019878: lysine biosynthetic process via aminoadipic acid biological_process
AuthorHaft DH
Entry DateMar 20 2001 4:31PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis very small, poorly characterized protein has been shown essential in Thermus thermophilus for an unusual pathway of Lys biosynthesis from aspartate by way of alpha-aminoadipate (AAA) rather than diaminopimelate. It is found also in Deinococcus radiodurans and Pyrococcus horikoshii, which appear to share the AAA pathway.
ReferencesRM 11238076 RT Distribution of genes for lysine biosynthesis through the aminoadipate pathway among prokaryotic genomes. RA Nishida H RL Bioinformatics 2001 Feb;17(2):189-91