HMM Summary Page: TIGR01196

Functionphosphogluconate dehydratase
Gene Symboledd
Trusted Cutoff708.25
Domain Trusted Cutoff708.25
Noise Cutoff349.50
Domain Noise Cutoff349.50
Isology Typeequivalog
EC Number4.2.1.12
HMM Length601
Mainrole CategoryEnergy metabolism
Subrole CategoryEntner-Doudoroff
Gene Ontology TermGO:0004456: phosphogluconate dehydratase activity molecular_function
GO:0009255: Entner-Doudoroff pathway biological_process
AuthorHaft DH
Entry DateMar 5 2001 1:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentA close homolog, designated MocB (mannityl opine catabolism), is found in a mannopine catabolism region of a plasmid of Agrobacterium tumefaciens. However, it is not essential for mannopine catabolism, branches within the cluster of 6-phosphogluconate dehydratases (with a short branch length) in a tree rooted by the presence of other dehydyatases. It may represent an authentic 6-phosphogluconate dehydratase, redundant with the chromosomal copy shown to exist in plasmid-cured strains. This HMM includes mocB above the trusted cutoff, although the designation is somewhat tenuous.
ReferencesRM 8655509
Genome PropertyGenProp0468: Entner-Doudoroff pathway (HMM)