| Accession | TIGR01188 |
| Name | drrA |
| Function | daunorubicin resistance ABC transporter, ATP-binding protein |
| Trusted Cutoff | 312.45 |
| Domain Trusted Cutoff | 312.45 |
| Noise Cutoff | 305.30 |
| Domain Noise Cutoff | 305.30 |
| Isology Type | subfamily |
| HMM Length | 302 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Other |
| Gene Ontology Term | GO:0005524: ATP binding molecular_function |
| | GO:0043190: ATP-binding cassette (ABC) transporter complex cellular_component |
| | GO:0043215: daunorubicin transport biological_process |
| | GO:0043216: daunorubicin-transporting ATPase activity molecular_function |
| Author | Ujwal ML, Paulsen IT |
| Entry Date | Mar 4 2001 10:57PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. |
