| Accession | TIGR01187 |
| Name | potA |
| Function | polyamine ABC transporter, ATP-binding protein |
| Trusted Cutoff | 355.60 |
| Domain Trusted Cutoff | 355.60 |
| Noise Cutoff | 349.95 |
| Domain Noise Cutoff | 349.95 |
| Isology Type | subfamily |
| EC Number | 3.6.3.31 |
| HMM Length | 325 |
| Mainrole Category | Transport and binding proteins |
| Subrole Category | Amino acids, peptides and amines |
| Gene Ontology Term | GO:0005524: ATP binding molecular_function |
| | GO:0009898: internal side of plasma membrane cellular_component |
| | GO:0015417: polyamine-transporting ATPase activity molecular_function |
| | GO:0015846: polyamine transport biological_process |
| | GO:0055052: ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing cellular_component |
| Author | Ujwal ML, Paulsen IT |
| Entry Date | Mar 4 2001 10:54PM |
| Last Modified | Dec 21 2011 12:51PM |
| Comment | This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). |
| References | DR HAMAP; MF_01726; 93 of 157 |
