| Accession | TIGR01173 |
| Name | glmU |
| Function | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase |
| Gene Symbol | glmU |
| Trusted Cutoff | 366.85 |
| Domain Trusted Cutoff | 366.85 |
| Noise Cutoff | 204.85 |
| Domain Noise Cutoff | 204.85 |
| Isology Type | equivalog |
| EC Number | 2.7.7.23 2.3.1.157 |
| HMM Length | 452 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of murein sacculus and peptidoglycan |
| Gene Ontology Term | GO:0003977: UDP-N-acetylglucosamine diphosphorylase activity molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0009103: lipopolysaccharide biosynthetic process biological_process |
| | GO:0009252: peptidoglycan biosynthetic process biological_process |
| | GO:0019134: glucosamine-1-phosphate N-acetyltransferase activity molecular_function |
| Author | Dodson RJ |
| Entry Date | Feb 15 2001 2:22PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein is a bifunctional enzyme, GlmU, which catalyzes last two reactions in the four-step pathway of UDP-N-acetylglucosamine biosynthesis from fructose-6-phosphate. Its reaction product is required from peptidoglycan biosynthesis, LPS biosynthesis in species with LPS, and certain other processes. |
| References |
DR HAMAP; MF_01631; 430 of 440 |
| Genome Property | GenProp0750: UDP-N-acetylglucosamine biosynthesis from fructose-6-phosphate (HMM) |
