HMM Summary Page: TIGR01173

FunctionUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase
Gene SymbolglmU
Trusted Cutoff366.85
Domain Trusted Cutoff366.85
Noise Cutoff204.85
Domain Noise Cutoff204.85
Isology Typeequivalog
EC Number2.7.7.23
HMM Length452
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of murein sacculus and peptidoglycan
Gene Ontology TermGO:0003977: UDP-N-acetylglucosamine diphosphorylase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0009103: lipopolysaccharide biosynthetic process biological_process
GO:0009252: peptidoglycan biosynthetic process biological_process
GO:0019134: glucosamine-1-phosphate N-acetyltransferase activity molecular_function
AuthorDodson RJ
Entry DateFeb 15 2001 2:22PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is a bifunctional enzyme, GlmU, which catalyzes last two reactions in the four-step pathway of UDP-N-acetylglucosamine biosynthesis from fructose-6-phosphate. Its reaction product is required from peptidoglycan biosynthesis, LPS biosynthesis in species with LPS, and certain other processes.
References DR HAMAP; MF_01631; 430 of 440
Genome PropertyGenProp0750: UDP-N-acetylglucosamine biosynthesis from fructose-6-phosphate (HMM)