HMM Summary Page: TIGR01160

Functiontranslation initiation factor SUI1
Trusted Cutoff143.90
Domain Trusted Cutoff143.90
Noise Cutoff47.90
Domain Noise Cutoff47.90
Isology Typeequivalog
HMM Length110
Mainrole CategoryProtein synthesis
Subrole CategoryTranslation factors
Gene Ontology TermGO:0003743: translation initiation factor activity molecular_function
GO:0005840: ribosome cellular_component
GO:0006413: translational initiation biological_process
AuthorHaft DH
Entry DateFeb 5 2001 4:13PM
Last ModifiedFeb 14 2011 3:27PM
CommentAlternate name: MOF2. A similar protein family (see TIGRFAMs model TIGR01158) is found in prokaryotes. The human proteins complements a yeast SUI1 mutatation.
ReferencesRM 10376878 RT Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay. RA Cui Y, Gonzalez CI, Kinzy TG, Dinman JD, Peltz SW RL RNA 1999 Jun;5(6):794-804